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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALOX5
All Species:
26.97
Human Site:
T259
Identified Species:
65.93
UniProt:
P09917
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09917
NP_000689.1
674
77983
T259
L
P
E
K
L
P
V
T
T
E
M
V
E
C
S
Chimpanzee
Pan troglodytes
XP_507763
906
101718
T383
L
P
E
K
L
P
V
T
R
N
G
L
I
F
G
Rhesus Macaque
Macaca mulatta
XP_001102354
674
77863
T259
L
P
E
K
F
P
V
T
T
E
M
V
E
C
S
Dog
Lupus familis
XP_534950
690
79170
T275
L
P
E
K
L
P
V
T
T
E
M
V
E
C
S
Cat
Felis silvestris
Mouse
Mus musculus
P48999
674
77981
T259
L
P
P
K
L
P
V
T
T
E
M
V
E
C
S
Rat
Rattus norvegicus
P12527
673
78069
T258
L
P
K
K
L
P
V
T
T
E
M
V
E
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423676
651
74206
T240
L
P
E
K
F
P
V
T
Q
E
M
V
A
D
S
Frog
Xenopus laevis
NP_001089265
670
75862
D259
I
P
D
N
F
P
V
D
D
V
T
V
S
A
I
Zebra Danio
Brachydanio rerio
XP_695587
674
78343
T259
I
P
D
K
F
P
V
T
H
N
I
V
E
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LUW0
886
101041
D414
F
P
P
K
S
C
L
D
S
A
K
Y
G
N
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.1
98
86
N.A.
93.1
92.8
N.A.
N.A.
44.6
41.3
74.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
71.4
98.9
91.3
N.A.
97.1
96.8
N.A.
N.A.
62
62.4
88.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
93.3
100
N.A.
93.3
93.3
N.A.
N.A.
73.3
26.6
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
93.3
100
N.A.
93.3
100
N.A.
N.A.
73.3
40
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
50
0
% C
% Asp:
0
0
20
0
0
0
0
20
10
0
0
0
0
20
0
% D
% Glu:
0
0
50
0
0
0
0
0
0
60
0
0
60
0
0
% E
% Phe:
10
0
0
0
40
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
20
0
0
0
0
0
0
0
0
0
10
0
10
0
10
% I
% Lys:
0
0
10
90
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
70
0
0
0
50
0
10
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
60
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
20
0
0
0
10
0
% N
% Pro:
0
100
20
0
0
90
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
0
10
0
0
0
10
0
70
% S
% Thr:
0
0
0
0
0
0
0
80
50
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
90
0
0
10
0
80
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _